Study of some immune responses in postnatally, malnourished rats.
نویسندگان
چکیده
Post weaning rats were fed protein deficient dies for about 6 weeks until their body weight/brain weight ratio started to decrease. Effect of such malnutrition on the plaque forming response of antibody producing spleen cells against three bacterial antigens, Vibrio cholerae, Salmonella paratyphii and Staphylococcus aureus were studied. Mitogen stimulation of spleen cells was also studied using phytohemagglutinin and H-thymidine. Antibody plaque forming cell number and spleen cell stimulation response to phytohemagglutinin decreased significantly (P<001) in the malnourished rats as compared to the controls(JPMA 34 : 270, 1984).
منابع مشابه
Influence of a multideficient diet from northeastern Brazil on resting blood pressure and baroreflex sensitivity in conscious, freely moving rats.
The "regional basic diet" or RBD is a multideficient diet (providing 8% protein) which is known to produce dietary deficiencies in some populations in northeastern Brazil. The present study investigated the effects of RBD-induced malnutrition on resting blood pressure and baroreflex sensitivity in conscious rats. Malnourished rats were obtained by feeding dams the RBD during mating and pregnanc...
متن کاملGlucose tolerance and insulin release in malnourished rats.
1. Young Wistar rats were used as an experimental model to determine the effects of protein-energy malnutrition on glucose tolerance and insulin release. 2. Malnourished rats presented some of the features commonly found in human protein-energy malnutrition, such as failure to gain weight, hypoalbuminaemia, fatty infiltration of the liver and intolerance of oral and intravenous glucose loads. 3...
متن کاملImmune Responses and some Blood Metabolite Responses of Female Holstein Calves to Dietary Supplementationwith Licorice Root (Glycyrrhiza glabra)
Different medicinal plants have been used in animal and poultry nutrition in last decade. It seems that there are some potential to these medicinal plants to replace with common antibiotics. Licorice root (Glycyrrhiza glabra) is a medicinal plant that extensively was used in different studies. In the present study, the effect of dietary addition of licorice root on performance and blood energy ...
متن کاملDeficient induction of the immune response to oral immunization with cholera toxin in malnourished rats during suckling.
Malnourished rats during suckling were orally immunized with cholera toxin (CT) after different periods of refeeding. Intestinal fluids, sera, and supernatant fluids from cultured mesenteric lymph node (MLN) cells were obtained after rats were given three doses of CT and analyzed by enzyme-linked immunosorbent assay (ELISA) to evaluate the specific antibody response. Serum-specific immunoglobul...
متن کاملEffects of Maternal Immune System Status on Neonate’s Immune System
Background: This study evaluated the effects of the maternal immune system stimulation or suppression during the pregnancy on the development of the neonate’s immune system.Methods: A total of 20 female rats were divided into four groups. The groups were treated using Leishmania major, Salmonella typhimurium, Tacrolimus, and sterilized normal saline. The animals were mated after 3-time tr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 34 9 شماره
صفحات -
تاریخ انتشار 1984